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December 11, 2018

Disabling a Cellular Antivirus System Could Improve Gene Therapy

An antivirus system that evolved eons ago in vertebrate cells helps to defend us against viruses. But it also vexes scientists. Whenever researchers try to insert foreign DNA into a cell’s nucleus—to study the function of a gene, or when trying to develop a gene therapy—the antivirus system silences the DNA.

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